AskDefine | Define ossification

Dictionary Definition



1 the developmental process of bone formation
2 the calcification of soft tissue into a bonelike material
3 the process of becoming rigidly fixed in a conventional pattern of thught or behavior
4 hardened conventionality [syn: conformity]

User Contributed Dictionary



  1. the normal process by which bone is formed
  2. the calcification of tissue into a bonelike mass; the mass so formed
  3. the process of becoming set in one's ways or beliefs; rigid conventionality

Extensive Definition

Ossification is the process of bone formation, in which connective tissues, such as cartilage are turned to bone or bone-like tissue. The ossified tissue is invaginated with blood vessels. These blood vessels bring minerals like calcium and deposit it in the ossifying tissue. Bone formation is a dynamic process, with cells called osteoblasts depositing minerals, and osteoclasts removing bone. This process, termed bone remodeling continues throughout life.

Types of ossification


Several hypotheses have been proposed for how bone evolved as a structural element in vertebrates. One popular idea is that bone developed from tissues that evolved to store minerals. In this model, minerals such as calcium were stored in cartilage, and that bone was an exaptation from this ossified cartilage. However, other possibilities include bony tissue evolving as an osmotic barrier, or as a protective structure.


ossification in Indonesian: Osifikasi
ossification in Japanese: 骨化
ossification in Swedish: Benbildning
ossification in Thai: การกลายเป็นกระดูก
ossification in Chinese: 成骨作用
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